Fri Dec 05 2025

44 articles - From Friday Nov 28 2025 to Friday Dec 05 2025

parm_toc.knit

Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…

J Crohns Colitis
Implementing the ECCO dietary consensus in IBD clinics: mind the gaps in restrictive eating and nutritional targets.

Pubmed   Journal   ReadQx 

Pancreas
Clinical Practice Guidelines for Pancreatic Cancer 2025 From the Japan Pancreas Society: A Synopsis.

These guidelines represent the most comprehensive and standardized resource currently available in Japan for the clinical management of pancreatic cancer. This English synopsis aims to disseminate the 2025 edition of the Japanese Clinical Practice Guidelines for Pancreatic Cancer to a global audience and highlight the Japanese approach to pancreatic cancer care.

Pubmed   Journal   ReadQx 


Meta-analysis

meta-analyses and systematic reviews

Am J Clin Nutr
Effect of early-life protein supplementation on childhood obesity and related metabolic outcomes: a systematic review and meta-analysis.

There is limited evidence of any impact of protein quantity or quality during complementary feeding on growth or body composition. Given the short-lasting exposures and follow-up times, the long-term metabolic effects of protein supplementation require further investigation.

Pubmed   Journal   ReadQx 

Optimal anthropometric discharge criteria from treatment of wasting: meta-analysis of individual patient data from 34 studies.

Relapse risk is high after successful MAM/SAM treatment. Future research can consider optimization of anthropometric discharge criteria as a strategy to reduce postdischarge relapse risk, weighing the operational and financial tradeoffs associated with any modification.

Pubmed   Journal   ReadQx 

Inflamm Bowel Dis
Risk Factors and Management of Incomplete Microscopic Colitis: A Systematic Review and Meta-Analysis.

Patients with MCi share similar characteristics with full MC including demographics, risk factors, and response to therapy, indicating that the histologic criteria for MC should potentially be broadened.

Pubmed   Journal   ReadQx 

The Risk of Relapse Associated With Discontinuation of 5-Aminosalicylates in Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis.

The discontinuation of oral or rectal 5-ASA monotherapy in patients with UC is associated with an increased risk of relapse. The data for discontinuation of 5-ASA in patients with UC or CD who are on immunomodulators and/or biologics is marginal for a meta-analysis; considering this limitation, these patients do not seem to have an increased risk of relapse upon discontinuation of 5-ASA, suggesting that monitored withdrawal may be a viable strategy.

Pubmed   Journal   ReadQx 

J Crohns Colitis
Apples and Oranges? Comparison of Early Ileocolic Resection and Medical Treatment for Crohn's Disease: A Systematic Review and Meta-analysis.

Pubmed   Journal   ReadQx 

Efficacy of 5-Aminosalicylic Acid Continuation versus Discontinuation in Patients with Ulcerative Colitis Escalated to Advanced Therapy: A Systematic Review and Meta-Analysis of Adjusted Effect Estimates.

In patients with UC escalated to advanced therapies, 5-ASA continuation was associated with decreased odds of achieving clinical remission compared to discontinuation, with no significant differences observed for secondary efficacy or safety endpoints.

Pubmed   Journal   ReadQx 

The global leadership initiative on malnutrition criteria for the diagnosis of malnutrition in patients with inflammatory bowel disease: a systematic review and meta-analysis.

The GLIM criteria demonstrate potential as an effective tool for diagnosing malnutrition in patients with IBD. However, further validation is necessary, requiring additional diagnostic accuracy studies to enhance their reliability and establish their clinical applicability.

Pubmed   Journal   ReadQx 


Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr
Development and validation of a brief Nutrition Security Screener (NSS) for clinical and public health settings.

A brief NSS enables assessment of NI prevalence and barriers to healthy eating in diverse populations, and is independently associated with diet-related disease, informing clinical, public health, and policy efforts to screen for and address NI.

Pubmed   Journal   ReadQx 

Eating Rate has Sustained Effects on Energy Intake from Ultra-Processed Diets: A Two-Week Ad Libitum Dietary Randomized Controlled Cross-over Trial.

Food texture-derived ER has a significant and sustained effect on energy intake of ultra-processed diets over a two-week period. This finding highlights the importance of food texture in guiding ER and the central role of sensory cues in regulating meal size. Clinical trial registry ClinicalTrials.gov Identifier NCT06113146.

Pubmed   Journal   ReadQx 

Gut microbes related to the Dietary Approaches to Stop Hypertension score are associated with bone quantity but not with bone quality in a cross-sectional study of older Puerto Rican adults.

DASH score was associated with hip BMD, but not with BMSi or TBS. Select diet-related gut microbes, and an inflammation score were associated with BMD. Future studies should examine dietary inflammation in relation to bone quality.

Pubmed   Journal   ReadQx 

Language Models in Nutrition and Dietetics: A Scoping Review.

In conclusion, this is an emerging area with limited evidence for real-world implementations or domain-specific models in nutrition and dietetics. Future work is required in real-world settings to strengthen this evidence base and to broaden it to incorporate the views of nutritionists, dietitians, people with medical conditions, and the general public.

Pubmed   Journal   ReadQx 

Male partner pesticide residue exposure from fruit and vegetable intake in relation to outcomes of infertility treatment: a prospective cohort study.

Intake of FVs with high pesticide residue in males is associated with adverse infertility treatment outcomes with ART, particularly in conventional insemination cycles. Implications for natural fertility are unclear.

Pubmed   Journal   ReadQx 

Post-malnutrition weight gain is associated with changes to muscle and energy metabolism in adolescence: a cohort analysis.

Individuals with greater PMWG exhibited lower muscle-related metabolites and altered energy metabolism in adolescence. It remains unclear whether this reflects inherent differences in how individuals gain weight, or whether early-life weight gain programs future metabolic states. Elucidating these mechanisms will inform interventions to ameliorate long-term health risks, an urgent priority following the growing double burden of malnutrition in low- and middle-income countries.

Pubmed   Journal   ReadQx 

Proteomics Networks Linking Diet to Cardiometabolic Risk Factors: The Framingham Heart Study.

Our findings highlight proteomic networks potentially linking diet and CVD risk and demonstrate the usefulness of proteomics for identifying high-risk individuals for future interventions.

Pubmed   Journal   ReadQx 

Reduction in Sugar Intake after the Introduction of Minimum Unit Pricing for Alcohol in Scotland: a Difference-in-Differences Analysis.

MUP in Scotland is associated with small, but beneficial, statistically significant reductions in the purchase of sugar. There is no significant change in overall diet quality.

Pubmed   Journal   ReadQx 

What Is "Healthy" Food? A Cross-Sectional Evaluation of Foods and Beverages Consumed by US Adults That Satisfy the US Food and Drug Administration's Updated "Healthy" Claim Criteria.

Findings suggest few foods met "healthy" criteria. Moderate correlations between "healthy" criteria, Nova, and validated nutrient profiling models provide evidence of convergent validity, yet underscore the challenge of classifying foods by healthfulness, and highlight uncertainty about whether discrepancies reflect real differences in model performance and food healthfulness.

Pubmed   Journal   ReadQx 

Inflamm Bowel Dis
Clinical Response for 12 Months or More to the First Advanced Therapy is Associated with a Significant Decrease in the Long-Term Risk of Hospitalization: A Nation-Wide Analysis of Patients From the UK Inflammatory Bowel Disease (IBD) BioResource.

Treatment response to the first advanced treatment initiated is significantly associated with a lower long-term risk of hospitalization for IBD. Choosing the best therapy the first time may improve long-term outcomes.

Pubmed   Journal   ReadQx 

Efficacy of Consistency Versus Switching of Biologics for Prevention of Postoperative Recurrence in Crohn's Disease: A Multicenter Real-World Retrospective Study.

In CD patients with preoperative biologic exposure, both continuing and switching biologic therapy postoperatively were effective in preventing ER, with switching showing improved endoscopic outcomes after adjustment for confounders.

Pubmed   Journal   ReadQx 

Intestinal Ultrasound for Monitoring Postoperative Crohn's Disease: A Review and Visual Atlas.

This review provides practical guidance for identifying the ileocolic anastomosis and its key sonographic landmarks. It also outlines techniques for assessing the anastomosis with grayscale IUS and discusses strategies for integrating IUS into routine postoperative surveillance of CD.

Pubmed   Journal   ReadQx 

Low Rates of Surgical Recurrence Following Ileocolic Resections for Crohn's Disease in the Biologic Era.

The rate of SR at the ileocolic anastomosis in this large Australian cohort was low, recorded to be 1 in 20 at 5 years. Smoking remains the strongest risk factor for both ER and SR. Histopathological factors influence ER and should be considered in future risk prediction models.

Pubmed   Journal   ReadQx 

Shared Genetic Basis Between Systemic Lupus Erythematosus and Inflammatory Bowel Disease in East Asian Ancestry: A Genome-Wide Cross-trait Analysis.

The major histocompatibility complex region emerges as a critical hub for shared genetic correlations and pleiotropic effects in SLE-IBD pathogenesis. Gene-level enrichment analyses implicate chemokine and lipid binding as underlying shared biological mechanisms.

Pubmed   Journal   ReadQx 

Short Ileal Microvillus Length Phenotype Associates with Progression from Inflammatory to Complicated Disease Behavior in Pediatric Crohn's Disease.

Short ileal MVL is associated with the development of complicated disease behaviors in pediatric CD, supporting the potential use of this histological phenotype as a biomarker for CD prognosis.

Pubmed   Journal   ReadQx 

J Crohns Colitis
Background Mucosal Inflammation Affects Colorectal Cancer Prognosis in Ulcerative Colitis: A Nationwide, Multicenter Study.

Background mucosal inflammation at cancer diagnosis is associated with significantly worse prognosis of CRC in UC patients. Systematic endoscopic assessment at cancer diagnosis may aid prognostic stratification and inform management.

Pubmed   Journal   ReadQx 

Cost-effective inflammatory bowel disease flare pathway with nurse-led triage and rapid access intestinal ultrasound reduces hospital resource use with high patient satisfaction.

Our novel CCP reduced hospital resource utilisation, with high patient satisfaction and significant cost savings.

Pubmed   Journal   ReadQx 

Cumulative Incidence and Risk Factors for Advanced Neoplasia following Inflammatory Bowel Disease-Related Low-Grade Dysplasia: A Danish Nationwide Cohort Study.

Among Danish individuals with IBD-related LGD, the overall 15-year cumulative incidence of subsequent HGD or CRC was 6.3% and has declined markedly over time. In addition to established risk factors, including age, IBD duration, family history of colorectal cancer, and elevated faecal calprotectin, we found that high-dose prednisone use was associated with an increased risk.

Pubmed   Journal   ReadQx 

Inflammatory Bowel Disease therapies and Demyelinating Diseases: A Practical Guide to Therapeutic Benefit and Risk.

It proposes a practical framework for clinicians, addressing management strategies for patients with confirmed MS, those at increased risk, and individuals who develop neurological symptoms during treatment. In the absence of formal guidelines, multidisciplinary collaboration, early recognition of symptoms, and careful treatment selection are important to optimise both gastrointestinal and neurological outcomes.

Pubmed   Journal   ReadQx 

Real-world evaluation of MRI fistula volume as a radiological biomarker of disease activity in perianal fistulising crohn's disease.

MRI fistula volume is associated with pfCD class and disease trajectory. Volume thresholds are associated with classification shifts and clinical response, supporting their potential as objective quantitative tools. Prospective multicentre validation is warranted.

Pubmed   Journal   ReadQx 

Liver Transpl
Baseline oral microbiome associated with post-living donor liver transplant early complications within 6 months.

Baseline oral microbiome profiles were differentially abundant among individuals who developed post-LT early complications. Incorporating microbial signatures may enable noninvasive risk stratification after LT.

Pubmed   Journal   ReadQx 

Pancreas
Episodic and Long-Term Costs of Acute Pancreatitis Requiring Hospitalization among Adults in US Clinical Practice.

The cost of AP requiring hospitalization is high, for the treatment of both acute disease as well as associated long-term complications, which underscores the potential economic benefits from the prevention of this condition.

Pubmed   Journal   ReadQx 

Pancreatology
Correlation between immune biomarkers and surrogate markers of severity of Acute Pancreatitis in an HIV endemic region.

Distinct immune signatures correlate with AP severity and are significantly influenced by HIV status. IL-15 outperformed IL-6, TNF-α, IL-17, and MCP-1 in people without HIV, whereas TNF-α was the only predictor of severity in PLWH. Higher thresholds for prediction of severity in PLWH underscore the need for HIV-specific biomarker thresholds and further research into tailored severity stratification, and development of immunomodulating therapies in AP.

Pubmed   Journal   ReadQx 

FBXO22-mediated ubiquitination of KLF10 promoting pancreatic cancer proliferation and invasion.

FBXO22 promotes pancreatic cancer progression by mediating KLF10 ubiquitination and degradation, thereby impairing its tumor-suppressive functions. FBXO22 may serve as a potential oncogenic and therapeutic target associated with pancreatic cancer progression.

Pubmed   Journal   ReadQx 

Serum autoantibody signatures enable non-invasive early detection of pancreatic cancer.

Our findings indicated that the rondom froest model based on five autoantibodies might help identify preclinical and early-stage PC.

Pubmed   Journal   ReadQx 


Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Am J Clin Nutr
Discharge criteria for treatment of wasting: thinking beyond anthropometry.

Pubmed   Journal   ReadQx 

Does higher protein intake influence risk of child obesity?

Pubmed   Journal   ReadQx 

Nutrition security: considerations for a new measure and beyond.

Pubmed   Journal   ReadQx 

Pancreatology
Pancreatic cancer: An urgent clinical challenges and opportunities for improved care.

Pubmed   Journal   ReadQx 


Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Am J Clin Nutr
AI and Machine Learning in Nutrition: The Promise, the Challenge, and Recommendations.

Pubmed   Journal   ReadQx 

Inflamm Bowel Dis
Evaluating Choice of Biologics for Isolated Small-Bowel Crohn's Disease.

Pubmed   Journal   ReadQx 

Liver Transpl
The Yin-yang of HCC management: Reconciling therapeutic hierarchy and transplant benefit in Real-World evidence.

Pubmed   Journal   ReadQx 


Letters&Replies

Letters to the editors and authors’ replies

Am J Clin Nutr
Nutrition and physical function in aging: measurement and modeling considerations.

Pubmed   Journal   ReadQx 

Pancreatology
Complete pathological response in metastatic pancreatic adenocarcinoma following neoadjuvant therapy.

Pubmed   Journal   ReadQx 

Reevaluating rifaximin prophylaxis in severe acute pancreatitis: A call for methodological refinement and microbiome-centric endpoints.

Pubmed   Journal   ReadQx